Bioavailable human metabolites from TOTUM-448 (plant-based formulation) maintain liver cell functionality in a hyperlipidic context that drives MASLD onset.

Sci Rep · 2025 · PMC12824265 · PMID 41402426

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closest p · 4.0× alpha

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did not reach statistical significancep = 0.2not close (p > 0.1)

In contrast, TOTUM-448 metabolites (EHS-P) tended to inhibit this phenomenon, although this result did not reach statistical significance (−29%, p = 0.2, Fig. 5 C).

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