Endothelial dysfunction in Fabry disease: retinal biomarkers link cardiac GLA gene variants with chronic inflammation.

NPJ Genom Med · 2026 · PMC12824269 · PMID 41545379

Europe PMC DOI

hedged sentences

0.1000

closest p · 2.0× alpha

0.1000

boldest claim

The sentences

failed to reach significancep = 0.10so close (0.05 < p ≤ 0.1)

Female FD patients had lower vFID (p = 0.030) as did male patients, which, however, failed to reach significance (p = 0.10).

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did not reach statistical significanceno p-value reported

There was a trend towards a higher frequency of Fabry-related comorbidities in patients with pathogenic, likely pathogenic, and VUS, though this did not reach statistical significance.

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