The C-reactive protein-triglyceride glucose index (CTI) predicts mortality in cardiovascular-kidney-metabolic syndrome: a dual-cohort study with machine learning validation.

Although the association between Q4 and cardiovascular mortality did not reach statistical significance (HR = 1.51, 95% CI: 0.98–2.31, P = 0.059), it approached the significance threshold and there was a significant dose-response trend ( P -trend = 0.008), suggesting that an elevated CTI may still be associated with an increased risk of cardiovascular mortality.

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