showed a trendp = 0.062
The A allele of SNP -278A/G showed a trend for significance in this group (p = 0.062; OR = 1.34).
The A allele of SNP -278A/G showed a trend for significance in this group (p = 0.062; OR = 1.34).
saw an association of the Valine allele in their cohort, its moderate effect combined with highly significant p-values for two SNPs located in intron 1 and the 3'UTR (rs737865 and rs165599) has led to the hypothesis that the Val/Met variant may not contribute to disease but may simply be in strong LD with the actual, as of yet unidentified pre-disposing variant [ 40 ].