Dissecting the relationship between hypertensive disorders of pregnancy and branched-chain amino acids: An integrated investigation combining Mendelian randomization, transcriptomics, and machine learning.

Medicine (Baltimore) · 2026 · PMC12826240 · PMID 41560044

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did not reach statistical significanceno p-value reported

Isoleucine levels (OR: 1.266, 95% CI: 1.054–1.521; P = .012) demonstrated a positive association with HDP risk that did not reach statistical significance after Bonferroni correction.

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