Case Report: Resolution of complete heart block following vitamin D supplementation in a child with Graves disease.

Front Endocrinol (Lausanne) · 2025 · PMC12827079 · PMID 41585809

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The largest randomized controlled trial to date, the DAGMAR trial, found that vitamin D supplementation (2800 IU daily) did not improve remission rates in Graves disease patients treated with antithyroid drugs and, paradoxically, showed a trend toward worse outcomes (42% failure rate versus 32% in placebo) ( 15 ).

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