Relationship between sleep disorders and the efficacy of immune checkpoint inhibitors in older patients with non-small cell lung cancer.

Front Oncol · 2025 · PMC12827081 · PMID 41584611

Europe PMC DOI

hedged sentence

0.1860

closest p · 3.7× alpha

0.1860

boldest claim

The sentences

did not reach statistical significanceP = 0.186not close (p > 0.1)

<1%) showed that the negative association between sleep disorders and ICI efficacy (CR/PR/SD) was more pronounced in the subgroup with PD-L1 expression < 1% (P = 0.001), while in the PD-L1 expression ≥1% subgroup, the association exhibited a similar trend but did not reach statistical significance (P = 0.186).

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