Barely Significant
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Effects of cannabidiol in alcohol use disorder patients with and without co-occurring post-traumatic stress disorder: Tolerability but no evidence for efficacy in two randomized proof-of-concept trials.

Alcohol Clin Exp Res (Hoboken) · 2026 · PMC12828103 · PMID 41312717

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nominally significantno p-value reported
Figure 4 displays scatterplots of the observed nominally significant associations of week 4 CBD levels with BDI‐II scores, PHDD, and DPD.

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possibly significantno p-value reported
derate to severe non‐nicotine substance use disorder or any current cannabis use disorder, current pregnancy or lactation, urine drug screen positive for THC, cocaine or opioids or current use of exclusionary medications, including any pharmacotherapy for alcohol use disorder or any medication with possibly significant pharmacokinetic interactions with CBD.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.