The "double-edged sword" effect of non-steroidal anti-inflammatory drugs (NSAIDs) in the treatment of endometriosis (EMS).

As shown in Table 4 , after rigorous Bonferroni and FDR correction, the causal associations for EPHB4 (p_bonferroni = 0.0018, p_fdr = 0.0009) (Supplementary Table 23) and PTGER4 (p_bonferroni = 1.687E-10, p_fdr = 1.687E-10) (Supplementary Table 28) remained highly significant.

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For other genes, including NDST1 (Supplementary Table 27), HINT1 (Supplementary Table 26), FDFT1 (Supplementary Table 25), and FABP2 (Supplementary Table 24), the associations did not reach statistical significance after correction.

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