Since smoking status was determined based on a one-time questionnaire, there may be significant recall bias and underreporting as well as changes in smoking intensity over time that are not reflected in our estimation of total PY.
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Early age at smoking initiation is associated with elevated cardiovascular disease and mortality risk in a nationwide population-based cohort.
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The sentences
While a recent cohort study demonstrated a significant trend of increasing stroke risk with younger age at smoking initiation over a ten-year follow-up 25 , no such association with stroke was identified in a birth cohort followed up for five decades 26 .