Effect of Nitisinone on Aortic Stenosis Disease Progression in Patients With Alkaptonuria: An Analysis of the Suitability of Nitisinone in Alkaptonuria (SONIA) 2 Study.

Cureus · 2025 · PMC12832065 · PMID 41589138

Europe PMC DOI

hedged sentence

0.2300

closest p · 4.6× alpha

0.2300

boldest claim

The sentences

did not reach statistical significancep=0.23not close (p > 0.1)

The difference in P max between the control (N=69) and treatment (N=69) groups at baseline was 0.063 mmHg [95% CI: -0.054 mmHg to 0.18 mmHg) and did not reach statistical significance (p=0.23).

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