Integrative subtyping by bile acid metabolism identifies CLCA1/UGT2A3/ZG16 as markers of immune dysfunction and poor prognosis in colorectal cancer.

Front Oncol · 2025 · PMC12832251 · PMID 41602387

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did not reach statistical significanceno p-value reported

Survival analysis showed that high CLCA1 expression was significantly associated with favorable overall survival ( p < 0.001), whereas UGT2A3 ( p = 0.23) and ZG16 ( p = 0.17) did not reach statistical significance.

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Integrative subtyping by bile acid metabolism identifies <i>CLCA1</i>/<i>UGT2A3</i>/<i>ZG16</i> as markers of immune dysfunction and poor prognosis in colorectal cancer.

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