SARS-CoV-2 evolution enhances endocytic uptake while preserving TMPRSS2-dependent fusion.

Front Immunol · 2025 · PMC12832645 · PMID 41601680

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showed a trendno p-value reported

Overall, the results showed a trend in which entry of clinical SARS-CoV-2 isolates via TMPRSS2-mediated membrane fusion into Calu-3 and Caco-2 cell lines remained relatively constant over the course of the pandemic.

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