Reduced global BOLD-CSF coupling in chronic kidney disease-related cognitive impairment: a resting-state functional MRI study.

Front Neurol · 2025 · PMC12832948 · PMID 41602980

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did not reach statistical significanceno p-value reported

Although the direct correlation between gBOLD-CSF coupling and MoCA scores did not reach statistical significance, the significant between-group differences strongly suggest that reduced glymphatic clearance efficiency is an important contributing factor to CI in patients with CKD.

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