Identification of Predictive Genomic Biomarkers in Metastatic Clear Cell Renal Cell Carcinoma: A Comprehensive Analysis of Real-World Clinicogenomic Data.

JCO Precis Oncol · 2026 · PMC12834269 · PMID 41576306

Europe PMC DOI

hedged sentence

0.6000

closest p · 12.0× alpha

0.6000

boldest claim

The sentences

did not reach statistical significanceP > .6not close (p > 0.1)

However, the test for interaction did not reach statistical significance ( P > .6). rwPFS in patients with WT PBRM1 and SETD2 favored ICI-C (for PBMR1 : HR = 0.73, P = .061; for SETD2 : HR = 0.70, P = .017), with no statistically significant interaction.

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