Barely Significant
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Impact of Open Proximal Contacts on Peri-Implant Diseases: A Systematic Review and Meta-Analysis.

Clin Exp Dent Res · 2026 · PMC12834509 · PMID 41587408

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an increasing trendno p-value reported
An increasing trend in proximal contact loss was observed over time (French et al. 2019 ; Ko et al. 2024 ; Latimer et al. 2021 ), with approximately 50% of contacts lost by 9 years after prosthesis delivery (Byun et al. 2015 ).

also in 63,971 other papers

This review demonstrated a trend toward greater marginal bone loss and increased probing pocket depths in sites with open proximal contacts; however, these differences did not reach statistical significance when compared to sites with closed contacts.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.