Diagnostic efficacy of blood biomarkers for differentiating early-stage pancreatic cancer from chronic pancreatitis: A systematic review and network meta-analysis.

Transl Oncol · 2026 · PMC12834843 · PMID 41547146

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Additionally, the panel combining CA199, trefoil factor 1 (TFF1), trefoil factor 2 (TFF2), and trefoil factor 3 (TFF3) showed a trend toward higher sensitivity compared to CA199, albeit with borderline statistical significance (OR 3.61, 95 % CI 0.84-17.48).

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