Barely Significant
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Activating PRKG1 Variant Enhances Smooth Muscle Cell Deformability to Cause Aortopathy.

JACC Basic Transl Sci · 2026 · PMC12834846 · PMID 41544301

Europe PMCDOI
1
hedged sentence
0.2000
closest p · 4.0× alpha
0.2000
boldest claim

The sentences

did not reach statistical significanceP = 0.20not close (p > 0.1)
Thus, PKG V219I hiPSC-VSMCs consistently displayed a reduced confluency with increasing stage of the differentiation procedure, although this did not reach statistical significance ( P = 0.20).

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