Longitudinal trajectories of cognitive decline and temporal lobe atrophy based on baseline gonadotropins and testosterone.

Although a stronger association between FSH and cognitive trajectories was observed in women (MMSE: β = −0.027, P = 0.009; ADAS-cog: β = 0.069, P = 0.020), the sex interaction did not reach statistical significance (MMSE: P -interaction = 0.503; ADAS-cog: P -interaction = 0.874) ( Figure 3 and Table 3 ).

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