Barely Significant
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Subclinical atrial fibrillation: Implications of recent trials for guideline updates?

World J Cardiol · 2026 · PMC12836068 · PMID 41607628

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a favorable trendno p-value reported
Importantly, the STROKESTOP trial provided randomized evidence that systematic screening for AF in an elderly population (aged 75-76 years) with intermittent ECG monitoring was feasible and safe, and although the reduction in stroke or SE did not reach conventional statistical significance, the intervention group demonstrated a favorable trend towards improved clinical outcomes, including fewer strokes and lower mortality[ 18 ].

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Although the stroke incidence was low at approximately 1% per patient-year in both groups, ischemic stroke, SE and the composite of stroke/SE were numerically lower in the edoxaban arm but did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.