Reducing low-dose exposure in helical TomoTherapy for locally advanced left-sided breast cancer with a deformable image registration-based dose-mimicking workflow.

J Appl Clin Med Phys · 2026 · PMC12836287 · PMID 41589547

Europe PMC DOI

hedged sentences

0.0500

closest p · 1.0× alpha

0.0640

boldest claim

The sentences

did not reach statistical significancep > 0.05actually significant

Regarding the ipsilateral lung, although the ID was lower in TOMO_FA (11.24 ± 2.03 Gy·L) compared to TOMO_ORI (12.23 ± 2.52 Gy·L), the difference did not reach statistical significance ( p > 0.05).

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approached but did not reach significancep = 0.064so close (0.05 < p ≤ 0.1)

However, this reduction reached statistical significance only in the TOMO_FA plans ( p = 0.027), while the reduction in TOMO_RE approached but did not reach significance ( p = 0.064).

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