Systemic adjuvant and perioperative chemotherapy following curative-intent liver metastasectomy in colorectal cancer-is it justified?

ESMO Gastrointest Oncol · 2025 · PMC12836588 · PMID 41647996

Europe PMC DOI

hedged sentence

0.1300

closest p · 2.6× alpha

0.1300

boldest claim

The sentences

did not reach statistical significanceP = 0.13not close (p > 0.1)

However, the difference in 5-year OS did not reach statistical significance (51.1% versus 41.9%, OR 0.73, P = 0.13).

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