Barely Significant
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Prognostic nutritional index as a prognostic marker in metastatic esophageal squamous-cell carcinoma treated with immune checkpoint inhibitor.

ESMO Gastrointest Oncol · 2025 · PMC12836714 · PMID 41647976

Europe PMCDOI
1
hedged sentence
0.0900
closest p · 1.8× alpha
0.0900
boldest claim

The sentences

showed a trendP = 0.09so close (0.05 < p ≤ 0.1)
In the ICI plus chemotherapy group, the high PNI group showed a trend toward longer PFS than the low PNI group [median 7.9 months (95% CI 4.2-9.5 months) versus 3.9 months (95% CI 2.7-8.1 months), P = 0.09; Figure 3 A], though not statistically significant.

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