Barely Significant
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Utility of <sup>18</sup>F-Florzolotau PET as a prognostic and monitoring biomarker in a memory clinic cohort.

Alzheimers Res Ther · 2025 · PMC12836907 · PMID 41413592

Europe PMCDOI
1
hedged sentence
0.0620
closest p · 1.2× alpha
0.0620
boldest claim

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showed a trendp = 0.062so close (0.05 < p ≤ 0.1)
In following separate Cox models adjusted for these factors, higher neocortical NEO tau burden showed a trend toward predicting progression in the entire cohort (HR = 1.36 per SUVR unit, 95% CI 0.98–1.87, p = 0.062; the top panel of Fig. 3 C) and was a significant independent predictor in the AD spectrum sub-cohort (HR = 1.62 per SUVR unit, 95% CI 1.09–2.42, p = 0.018; the top panel of Fig. 3 E).

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