Natural Product Driven Activation of UCP1 and Tumor Metabolic Suppression: Integrating Thermogenic Nutrient Competition with Cancer Metabolic Reprogramming.

Biomolecules · 2026 · PMC12839171 · PMID 41594630

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In human human interventional study, daily ingestion of 9 mg capsinoids for 6 weeks increased supraclavicular BAT vascular density and showed a trend toward higher resting energy expenditure, indicating activation of UCP1-positive adipose depots [ 33 ]. 4.2.

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