Integrative Epigenomic and Transcriptomic Profiling Define Malignancy- and Cluster-Specific Signatures in Pheochromocytomas and Paragangliomas.

Cells · 2026 · PMC12839883 · PMID 41597272

Europe PMC DOI

hedged sentence

0.1190

closest p · 2.4× alpha

0.1190

boldest claim

The sentences

did not reach statistical significancep = 0.119not close (p > 0.1)

Among the differentially methylated genes, DSCAML1 exhibited higher expression in cluster II compared to cluster I, although this difference did not reach statistical significance (FC = +2, p = 0.119).

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