AI-Based Brain Volumetry Without MPRAGE? Evaluation of Synthetic T1-MPRAGE from 2D T2/FLAIR.

Diagnostics (Basel) · 2026 · PMC12840371 · PMID 41594294

Europe PMC DOI

hedged sentence

0.0686

closest p · 1.4× alpha

0.0686

boldest claim

The sentences

did not reach statistical significancep = 0.0686so close (0.05 < p ≤ 0.1)

Among subcortical structures, the amygdala ( p = 0.0018) and brainstem ( p < 0.001) exhibited significant differences, whereas the volume differences in the hippocampus did not reach statistical significance ( p = 0.0686). 3.4.2.

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