Modulation of the miR-485-3p/PGC-1α Pathway by ASO-Loaded Nanoparticles Attenuates ALS Pathogenesis.

Int J Mol Sci · 2026 · PMC12840692 · PMID 41596266

Europe PMC DOI

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0.0686

closest p · 1.4× alpha

0.0686

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The sentences

showed a trendp = 0.0686so close (0.05 < p ≤ 0.1)

In post hoc analyses, BMD-001S–treated SOD1 G93A mice showed a trend toward an increased proportion of fully innervated NMJs, with an approximately two-fold increase compared to vehicle-treated SOD1 G93A controls ( p = 0.0686).

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