Monopolar Radiofrequency for Facial Hyperpigmentation Treatment: An Integrated Retrospective Clinical Trial and Ex Vivo Study.

Int J Mol Sci · 2026 · PMC12841156 · PMID 41596410

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did not reach statistical significanceno p-value reported

For the lower cheek, although melanin level did not reach statistical significance, it followed a clear decreasing trend over 16 weeks.

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