Variants in <i>IRF5</i> Increase the Risk of Primary Sjögren's Syndrome in the Mexican Population.

Overall, while the combination of risk alleles in the TCAT haplotype increases the haplotype OR to 3.91 compared with the individual ORs of each variant (2.06, 1.76, 1.55, and 1.66, respectively), this association did not reach statistical significance, underscoring the dominant contribution of rs2004640T to pSS risk.

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