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Impact of Isosorbide Diesters from Coconut and Sunflower Fatty Acids on Pediatric Atopic Dermatitis and the Skin Microbiome: A Randomized, Double-Blind, Vehicle-Controlled Trial.

J Clin Med · 2026 · PMC12842038 · PMID 41598765

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Participants in the IDEAS group demonstrated a higher proportion achieving EASI50 and EASI75 at week 8 compared with vehicle, including a 42.9% EASI75 response, although these differences did not reach statistical significance, likely due to limited sample size.

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