Anti-Neuroinflammatory Effects of a Representative Low-Molecular-Weight Component Isolated from <i>Codium fragile</i> Through Inhibition of the NF-κB Pathway in Microglia and Macrophage Cells.

In BV2 microglia, LPS significantly decreased the IL-10 relative to the control group, whereas co-treatment with AECF or uracil showed a restorative upward trend toward the baseline; however, the difference versus the LPS-treated group did not reach statistical significance ( Figure 4 B).

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In contrast, in BV2 microglial cells, although an increasing trend in IL-10 production was observed under the same treatment conditions, the changes did not reach statistical significance.

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