Efficacy and Safety of Pirfenidone in Patients with Progressive Pulmonary Fibrosis: A Retrospective Single-Center Study.

Life (Basel) · 2025 · PMC12843490 · PMID 41598167

Europe PMC DOI

hedged sentences

0.0620

closest p · 1.2× alpha

0.0620

boldest claim

The sentences

showed a trendp = 0.062so close (0.05 < p ≤ 0.1)

DLco showed a trend toward improvement (−4.34 vs. +0.79% predicted; p = 0.062), while 6MWD significantly improved (−15.9 vs. +14.2 m; p = 0.024).

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a favorable trendno p-value reported

Therefore, although the observed change may indicate a favorable trend in physical performance, its clinical relevance should be interpreted with caution.

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