Microbiome and Skin Health: A Systematic Review of Nutraceutical Interventions, Disease Severity, Inflammation, and Gut Microbiota.

showed that, in a cohort of 28 patients, a 12-week supplementation with a probiotic significantly reduced TLC from 72.93 ± 10.11 to 33.57 ± 4.77 (Δ = −53.97 ± 10.04), a change that was highly significant compared to placebo (Δ = −4.29 ± 12.58, p = 0.002) [ 18 ].

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Although similar reductions were reported in another study by Eguren et al., the difference between groups did not reach statistical significance ( p = 0.06) [ 93 ]. 3.4.2.

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