A Nanoparticle-Based Strategy to Stabilize 5-Azacytidine and Preserve DNA Demethylation Activity in Human Cardiac Fibroblasts.

Pharmaceutics · 2026 · PMC12845215 · PMID 41599195

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did not reach statistical significanceno p-value reported

Although DNMT1 expression levels were consistently lower in the 5-Aza-NP group compared with free 5-Aza across storage temperatures, this difference did not reach statistical significance in direct pairwise comparisons.

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