Comprehensive Transcriptomic Profiling Reveals Rotavirus-Induced Alterations in Both Coding and Long Non-Coding RNA Expression in MA104 Cells.

Conversely, the interference of lncRNA6479 appeared to inhibit RV replication, although this inhibitory effect did not reach statistical significance ( Supplementary Figures S3–S5 ).

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This finding is highly significant, as it suggests that lncRNAs acting distally (via RBP binding or other complex formation) play a major role in coordinating the large-scale, functional immune response [ 43 ].

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