Identification of cancer-associated fibroblast signature genes for potential biomarkers in cholangiocarcinoma: a Mendelian randomization study.

Discov Oncol · 2025 · PMC12847485 · PMID 41436681

Europe PMC DOI

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closest p · 1.0× alpha

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did not reach statistical significanceP > 0.05actually significant

RT-PCR results indicated significantly elevated GRN and ORMDL3 mRNA expression in the ca group relative to the cap group (P < 0.05), whereas PLXNC1 expression exhibited an upward trend that did not reach statistical significance (P > 0.05).

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