Barely Significant
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Portrayed the development of activated T cell to exhausted T cell based on the ratio of CD28 to CTLA4.

Cancer Immunol Immunother · 2026 · PMC12847549 · PMID 41591572

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2 A-B did not reach statistical significance, a limitation likely attributed to the small sample size of the cohorts analyzed.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.