Prognostic value of ctDNA-derived maximum somatic allele frequency in patients with metastatic gastric cancer.

Ther Adv Med Oncol · 2026 · PMC12847658 · PMID 41613361

Europe PMC DOI

hedged sentences

0.1000

closest p · 2.0× alpha

0.1000

boldest claim

The sentences

a nonsignificant trendp = 0.1so close (0.05 < p ≤ 0.1)

PFS showed a nonsignificant trend favoring the MSAF-low group (median PFS, 4.5 vs 8.0 months; p = 0.1).

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did not reach statistical significanceno p-value reported

Treatment with immunotherapy-containing regimens showed a borderline association with better OS (HR, 0.40; 95% CI: 0.16–1.02, p = 0.054), although this did not reach statistical significance.

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