PR inhibition stimulates G6PD expression to enhance malignancy in luminal breast cancer.

Cell Death Dis · 2025 · PMC12847734 · PMID 41423458

Europe PMC DOI

hedged sentence

0.0000

closest p · 0.0× alpha

0.0000

boldest claim

The sentences

highly significantp = 2.63E-06actually significant

a clear trendp = 0.0939so close (0.05 < p ≤ 0.1)

The upregulation of G6PD and PGLS in the PR Low divergent group was highly significant ( p = 2.63E-06 and p = 9.78E-05), and PGD and RPIA also showed a clear trend of increased expression ( p = 0.0939 and p = 0.1170), contributing to a more pronounced overall activation pattern of the pathway (Fig.

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