Thrombomodulin facilitates melanoma progression via FAK- and ezrin-mediated phenotypic plasticity.

In addition, a trend toward an inverse correlation was observed between overall survival in melanoma patients and the mRNA expression levels of TM (gene symbol THBD) and its associated molecules, including ezrin (EZR) and FAK (PTK2), as well as their combined expression, although these analyses did not reach statistical significance (Figure S1).

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