Unveiling relative lymphopenia and elevated monocyte-to-lymphocyte count as novel independent adverse prognostic factors in chronic myelomonocytic leukemia (CMML)-Proposal of the objective prognostic index for CMML (OPIC).

Hemasphere · 2026 · PMC12849217 · PMID 41613280

Europe PMC DOI

hedged sentence

0.0750

closest p · 1.5× alpha

0.0750

boldest claim

The sentences

showed a trendP = 0.075so close (0.05 < p ≤ 0.1)

Additionally, MD‐CMML patients with MLR > 1 showed a trend toward a higher prevalence of CBL mutations (17.9% vs. 6.7%; P = 0.075).

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