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Pre-COVID-19 ex vivo cross-reactive IFN-γ cellular response to SARS-CoV-2 spike overlapping peptides is more prevalent among Kenyan compared to Swedish adults.

BMC Infect Dis · 2026 · PMC12849388 · PMID 41547725

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The frequencies for SARS-CoV-2 spike-specific TNF-α CD4+, TNF-α CD8 + and IFN- γ CD8 + T-cell responses, tended to be higher in the Kenyan adults although these differences did not reach statistical significance.

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