Integrated transcriptomic and functional analysis reveals overlapping pathways in lung adenocarcinoma and chronic obstructive pulmonary disease.

Low expression levels of SYNE1, SULT1A1, and FAM76A were significantly associated with poor OS (HR = 0.6, 0.61, and 0.58, respectively; P < 0.002), while COL10A1 showed a trend toward good prognosis (HR = 1.25; P = 0.019) (Fig. 3 A).

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