Rhythm-specific heart rate thresholds during the vulnerable period: integrated analysis for prognostic optimization in heart failure.

However, these associations failed to reach statistical significance in the pooled estimates (all-cause mortality: HR = 1.20, 95%CI: 0.98–1.46; readmission: HR = 1.25, 95%CI: 0.88–1.79), likely attributable to the limited number of qualifying studies and substantial heterogeneity (I 2 > 72%) that constrained analytical power despite rigorous methodology and absence of detectable publication bias (Begg’s P = 0.368, Egger’s P = 0.080).

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