Analysis of surface markers on T cells in sputum showed a trend towards an increase in the tissue-residency markers CD69 and CD103 after 12 months of ETI treatment, which could possibly suggest enhanced localization or retention of T cells within the airway mucosa (Fig. 3 G).
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Systemic and airway T cell dynamics with influenza-specific immune recovery by cystic fibrosis elexacaftor/tezacaftor/ivacaftor therapy.
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