Targeted chondrogenic differentiation of human MSCs using niosomes for SOX9 gene delivery: comparison of minicircle and conventional plasmids.

Stem Cell Res Ther · 2025 · PMC12849684 · PMID 41444958

Europe PMC DOI

hedged sentence

0.2400

closest p · 4.8× alpha

0.2400

boldest claim

The sentences

did not reach statistical significancep = 0.24not close (p > 0.1)

MC complexes (42.3 ± 1.6 mV) were consistently more electropositive than their PP counterparts (35.4 ± 1.3 mV; always p < 0.05), except those DP80CH nioplexes formed at a DOTMA/DNA ratio of 10/1, where this difference did not reach statistical significance ( p = 0.24).

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