Multiscale proteomic modeling reveals protein networks driving Alzheimer's disease pathogenesis.

Cell · 2025 · PMC12851831 · PMID 41005309

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closest p · 2.2× alpha

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The sentences

did not reach statistical significancep = 0.11not close (p > 0.1)

All seven KDPs exhibited expression patterns (i.e., upregulation or downregulation) consistent with those observed in the proteomic profiling except that the downregulation of NRN1 in AD did not reach statistical significance ( p = 0.11) ( Data S1 , pages 4A–4C; Table S6 , page 1).

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