The ROOT-CTRCD study: exploring the relationship of oral health to cancer therapy-related cardiac dysfunction in HER2-positive breast cancer patients.

Cardiooncology · 2026 · PMC12853818 · PMID 41519872

Europe PMC DOI

hedged sentences

0.0820

closest p · 1.6× alpha

0.0820

boldest claim

The sentences

a trend toward significancep = 0.082so close (0.05 < p ≤ 0.1)

Elevated troponin levels were seen in 22.5% of patients with poor oral health (9/40) versus 4.5% in the good oral health group (1/22), with a trend toward significance ( p = 0.082).

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did not reach statistical significanceno p-value reported

While the analysis of CTRCD severity did not reach statistical significance, a numerically higher proportion of patients with poor oral health were observed in the severe CTRCD subgroup (72.7%) compared to the mild group (62.7%).

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