Accelerated evolution in networked metapopulations of <i>Pseudomonas aeruginosa</i>.

It is possible that since our ancestral strain (PA14) has a propensity to produce biofilms (and we find putative mutations upregulating biofilm formation in the c-GMP pathway in our evolved metapopulations), our estimates of OD in exponential phase are more variable than they might otherwise be, which could explain why the statistical tests are close to but not quite significant.

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However, some key differences in fitness improvement (e.g., in growth rate) are only marginally significant, and the implications of this should be more explicitly discussed.

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